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From the Midwest to the Mission: Advancing National Security from America’s Heartland

BACKGROUND

​The Midwest Defense Innovation Summit (MDIS) is the region's premier gathering for advancing national security through cutting-edge innovation. Powered by the Applied Research Institute, this high-impact summit convenes policymakers, industry leaders, defense stakeholders, and regional partners to explore the latest advancements and emerging opportunities in artificial intelligence and beyond.

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MDIS 2025 has been postponed at the Grand Hall Ballroom at Crowne Plaza Union Station, located in the heart of downtown Indianapolis. Please stay up-to-date with our email list to learn about the new dates!

WHAT TO EXPECT

HOW TO STAY CONNECTED

This year’s summit will feature a series of keynote addresses and panel discussions, focused on the transformative role of artificial intelligence. 

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Our full speaker lineup and session details will be announced soon - stay tuned for an agenda designed to inform, inspire, and drive impact.

Stay Ahead of the Curve: Gain insight into the latest trends, technologies, and policy developments shaping the future of defense and national security.

Collaborate and Innovate: Engage with top minds across government, industry, and academia to spark partnerships and accelerate solutions.

Shape the Future: Be part of the critical conversations that will define the next era of American defense and innovation.

REGISTRATION

Two days, one ticket. Every attendee must have their own registration; if attending in group, each member will need to register. Please note: there will be no onsite registration available.

Register

SPEAKERS & PANELS

We’re excited to introduce an outstanding lineup of speakers for the Midwest Defense Innovation Summit (MDIS) 2025, happening October 15–16 at the Crowne Plaza Union Station in Indianapolis. This powerhouse group includes pioneers in defense, artificial intelligence, life and bio sciences, biosecurity, government and more, ready to deliver game-changing insights on AI, advanced manufacturing, and the future of national security.
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Join us to connect with these thought leaders and shape the future of defense innovation. Early bird registration is open. 

MEET THE SPEAKERS
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